LETTER	Synlett 2002: 0116-0118 DOI: 10.1055/s-2002-19338
© Georg Thieme Verlag Stuttgart · New York
Catalytic Synthesis of Sulfoximines using Copper(II) Salts
Emmanuel Lacôte, Muriel Amatore, Louis Fensterbank, Max Malacria*
UMR 7611, Université Pierre et Marie Curie, 4, Place Jussieu, b. 229, 75005 Paris, France Fax: +33(144)277360; e-Mail: malacria@ccr.jussieu.fr;
Received 28 September 2001

Abstract

The reaction of PhI=NTs with sulfoxides in the presence of catalytic amounts of copper(II) salts afforded the corresponding N-tosylsulfoximines in high yield. This method is highly tolerant to reaction conditions (no need of distilled solvents and/or inert atmospheres) and allowed the formation of previously unknown acetylenic sulfoximines with complete retention of configuration at sulfur.

Key words

asymmetric synthesis - catalysis - copper - sulfoxides - sulfur