PAPER	Synthesis 2002: 0733-0738 DOI: 10.1055/s-2002-25760
© Georg Thieme Verlag Stuttgart · New York
2-Acylpyridazin-3-ones: Novel Mild and Chemoselective Acylating Agents for Amines
Young-Jin Kang, Hyun-A Chung, Jeum-Jong Kim, Yong-Jin Yoon*
Department of Chemistry and Research Institute of Natural Sciences, Gyeongsang National University, Chinju 660-701, Korea Fax: +82(55)7610244; e-Mail: yjyoon@nongae.gsnu.ac.kr;
Received 7 January 2002

Abstract

2-Acyl-4,5-dichloropyridazin-3-ones served as excellent novel N-acylating reagents for amines under neutral conditions in organic solvent. They are convenient, chemoselective and easy to handle stable N-acylating reagents of amines.

Key words

2-acylpyridazin-3-one - chemoselective N-acylation - pyridazinone