PAPER	Synthesis 2002: 0784-0788 DOI: 10.1055/s-2002-25775
© Georg Thieme Verlag Stuttgart · New York
Iodine-Catalyzed, Efficient and Mild Procedure for Highly Chemoselective Acetalization of Carbonyl Compounds under Neutral Aprotic Conditions
Babak Karimi*, Behzad Golshani
Department of Chemistry, Institute for Advanced Studies in Basic Sciences (IASBS), P.O.Box 45195-159, Gava Zang, Zanjan, Iran Fax: +98(241)4249023; e-Mail: Karimi@iasbs.ac.ir;
Received 2 January 2002

Abstract

Various types of carbonyl compounds are efficiently converted to their 1,3-dioxanes by the use of 1,3-bis(trimethylsiloxy)propane (BTSP) and a catalytic amount of iodine (3-7 mol%) under essentially neutral aprotic condition.

Key words

carbonyl compounds - chemoselectivity - protection - 1,3-bis(trimethylsiloxy)propane - iodine