PAPER	Synthesis 2002: 2254-2258 DOI: 10.1055/s-2002-34848
© Georg Thieme Verlag Stuttgart · New York
Ring Opening of Epoxides and Aziridines with Sodium Azide using Oxone® in Aqueous Acetonitrile: A Highly Regioselective Azidolysis Reaction [1]
Gowravaram Sabitha*, R. Satheesh Babu, M. Shashi Kumar Reddy, J. S. Yadav
Organic Division I, Indian Institute of Chemical Technology, Hyderabad 500 007, India
Received 16 March 2002

Abstract

A wide variety of epoxides and aziridines were converted to the corresponding β-azido alcohols and β-azido amines with sodium azide using Oxone^® in aqueous acetonitrile. The reactions were highly regioselective and efficient with excellent yields at room temperature under mild reaction conditions.

Keywords

Oxone^® - epoxides - aziridines - azides - regioselectivity

1

IICT communication No. 03/02/02.