SHORTPAPER	Synthesis 2003: 2295-2297   DOI: 10.1055/s-2003-41055
© Georg Thieme Verlag Stuttgart · New York
Mild and Efficient Hydrolysis of Aromatic Thioacetals/Thioketals using o-Iodoxybenzoic acid (IBX) in Presence of β- Cyclodextrin in Water
N. Srilakshmi Krishnaveni, K. Surendra, Y. V. D. Nageswar, K. Rama Rao*
Organic Chemistry Division-I, Indian Institute of Chemical Technology, Hyderabad-500 007, India e-Mail: ramaraok@iict.res.in;
Received 21 May 2003

Abstract

An efficient and user-friendly procedure has been developed for the hydrolysis of thioacetals/thioketals to the corresponding carbonyl compounds in impressive yields with o-iodoxybenzoic acid (IBX) in presence of β-cyclodextrin (β-CD) in water under neutral conditions at room temperature.

Key Words

hydrolysis - thioacetals - thioketals - o-iodoxybenzoic acid - β-cyclodextrin - water