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| SHORTPAPER | Synthesis 2003: 2763-2764
DOI: 10.1055/s-2003-44354 |
© Georg Thieme Verlag Stuttgart · New York
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One-Pot Synthesis of 3-Substituted Isoxazoles from Phenyl Vinylic Selenide
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| Shou-Ri Sheng*, Xiao-Ling Liu, Qu Xu, Cai-Sheng Song |
Department of Chemistry, Jiangxi Normal University, Nanchang, 330027, P. R. China
Fax: +86(791)8517500; e-Mail: shengsr@163.com;
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Received
13 August 2003 |
Abstract
Phenyl vinylic selenide was adopted for 1,3-dipolar cycloaddition to nitrile oxides and subsequent oxidation-elimination furnished 3-substituted isoxazoles with good yields in a one-pot, two-step transformation. Key words
isoxazoles - phenyl vinylic selenide - 1,3-dipolar cycloaddition - oxidation-elimination
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