PAPER	Synthesis 2004: 568-572   DOI: 10.1055/s-2004-815944
© Georg Thieme Verlag Stuttgart · New York
A Simple and Facile Carboxylation Method and Its Application for Synthesis of Liquid Crystals
Adam Shih-Yuan Lee*, Chih-Chiang Wu, Li-Shin Lin, Hsiu-Fu Hsu
Department of Chemistry, Tamkang University, Tamsui, Taiwan Fax: +886 (2)26223830; e-Mail: adamlee@mail.tku.edu.tw;
Received 25 November 2003

Abstract

Sonication of a mixture of magnesium powder, 1,2-dibromoethane, aryl bromide and diethyl dicarbonate in THF followed by treatment with BF₃·OEt₂ at room temperature afforded aryl ester with reasonable yield. A series of aryl bromides were investigated and transformed to their corresponding aryl esters under the reaction conditions.

Key words

carboxylation - Barbier reaction - diethyl dicarbonate - Lewis acid - liquid crystal