PAPER	Synthesis 2004: 923-927   DOI: 10.1055/s-2004-815996
© Georg Thieme Verlag Stuttgart · New York
P-BEMP: A New Efficient and Commercially Available User-Friendly and Recyclable Heterogeneous Organocatalyst for the Michael Addition of 1,3-Dicarbonyl Compounds
David Bensa, Thierry Constantieux*, Jean Rodriguez*
UMR CNRS 6178 - SYMBIO Equipe RéSO, Réactivité en synthèse Organique, Univ. D'Aix-Marseille - Faculté des Sciences et techniques de Centre de St Jérôme - Case D12, 13397 Marseille Cedex 20, France Fax: +33(4)91288841; e-Mail: jean.rodriguez@univ.u-3mrs.fr;
Received 23 October 2003

Abstract

Michael addition of 1,3-dicarbonyls with various Michael acceptors has been found to be catalyzed by commercially available, user-friendly and recyclable N-phenyl-tris(di-methylamino)iminophosphorane immobilized on polystyrene resin (P-BEMP). The reaction does not require anhydrous solvents or inert atmosphere and proceeds smoothly at room temperature leading to the corresponding adducts, which can be conveniently isolated in high yield and with high chemical purity by simple filtration.

Key words

1,3-dicarbonyls - heterogeneous catalysis - Michael addition - polymer supported iminophosphoranes