 |
Original Article
| Endoscopy 2004; 36: 1094-1098
DOI: 10.1055/s-2004-826040 |
© Georg Thieme Verlag KG Stuttgart · New York |
| |
 |
Narrow-Band Imaging in the Diagnosis of Colorectal Mucosal Lesions: A Pilot Study |
| |
| H. Machida1, Y. Sano1, Y. Hamamoto1, M. Muto1, T. Kozu2, H. Tajiri3, S. Yoshida1 |
1 Division of Digestive Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, Japan
2 Division of Endoscopy, National Cancer Center Hospital, Tokyo, Japan
3 Department of Endoscopy, The Jikei University School of Medicine, Tokyo, Japan |
Background and Study Aims: A newly developed narrow-band imaging (NBI) technique, in which modified optical filters were used in the light source of a video endoscope system, was applied during colonoscopy in a clinical setting. This pilot study evaluated the clinical feasibility of the NBI system for evaluating colorectal lesions.
Patients and Methods: A total of 43 colorectal lesions in 34 patients were included in the study. The quality of visualization of colorectal lesions and the accuracy of differentiation between neoplastic and non-neoplastic lesions using the NBI system were evaluated in comparison with results from conventional colonoscopy and with chromoendoscopy.
Results: For pit pattern delineation, NBI was superior to conventional endoscopy (P < 0.001), but inferior to chromoendoscopy (P < 0.05). NBI achieved better visualization of the mucosal vascular network and of the hue of lesions than conventional endoscopy (P < 0.05). However there was no significant difference between NBI and chromoendoscopy in differentiating neoplastic from non-neoplastic lesions (both techniques had a sensitivity of 100 % and a specificity 75 %). This was better than the results of conventional colonoscopy (sensitivity 83 %, specificity 44 %; P < 0.05 for specificity).
Conclusions: These results suggest that in the examination of colonic lesions the NBI system provides imaging features additional to those of both conventional endoscopy and chromoendoscopy. For distinguishing neoplasms from non-neoplastic lesions, NBI was equivalent to chromoendoscopy.
| |
