PAPER	Synthesis 2004: 2381-2385   DOI: 10.1055/s-2004-831185
© Georg Thieme Verlag Stuttgart · New York
Silver Phosphotungstate: A Novel and Recyclable Heteropoly Acid for Friedländer Quinoline Synthesis
J. S. Yadav*, B. V. S. Reddy, P. Sreedhar, R. Srinivasa Rao, K. Nagaiah
Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad-500 007, India Fax: +91(40)27160512; e-Mail: yadav@iict.res.in;
Received 26 March 2004

Abstract

o-Aminoaryl ketones undergo smooth condensation with α-methylene ketones on the surface of silver heteropoly acid (Ag₃PW₁₂O₄₀) under mild reaction conditions to afford the corresponding polysubstituted quinolines in excellent yields with high selectivity. The catalyst can be recovered by simple filtration and can be recycled in subsequent reactions.

Keywords

heteropoly acids - o-aminoaryl ketones - α-methylene ketones - quinolines