SHORTPAPER	Synthesis 2004: 2959-2961   DOI: 10.1055/s-2004-834919
© Georg Thieme Verlag Stuttgart · New York
1,3-Dibromo-5,5-Dimethylhydantoin [DBDMH] as an Efficient and Selective Agent for the Oxidation of Thiols to Disulfides in Solution or under Solvent-Free Conditions
Ardeshir Khazaei*, Mohammad Ali Zolfigol, Amin Rostami
Department of Chemistry, Faculty of Science, Bu-Ali Sina University, P.O. Box 65174-4119, Hamedan, Iran e-Mail: a_khazaei@basu.ac.ir;
Received 11 June 2004

Abstract

A useful method for oxidation of various thiols to their corresponding disulfides with 1,3-dibromo-5,5-dimethylhydantoin (DBDMH) in very short reaction times and mild conditions under both solution and solvent-free conditions is described.

Keyword

1,3-dibromo-5,5-dimethylhydantoin - oxidation - thiol - disulfide