LETTER	Synlett 2005: 0997-0999   DOI: 10.1055/s-2005-864818
© Georg Thieme Verlag Stuttgart · New York
A Facile and Eco-Friendly Method for the Synthesis of 1,2-Orthoesters of Carbohydrates in Ionic Liquid
K. V. Radhakrishnan*, V. S. Sajisha, Jessy Maria Chacko
Organic Chemistry Section, Chemical Sciences Division, Regional Research Laboratory (CSIR), Trivandrum 690519, India Fax: +91(471)2491712; e-Mail: radhupreethi@rediffmail.com;
Received 12 December 2004

Abstract

A facile method for the synthesis of 1,2-orthoesters of carbohydrates in ionic liquid [bmim]PF₆ is described. The method described herein is simpler, eco-friendly and avoids the addition of quaternary ammonium salts as promoters.

Key words

ionic liquid - 1,2-orthoesters - carbohydrates - glycosyl bromides - quaternary ammonium salts