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| PAPER | Synthesis 2005: 2151-2156
DOI: 10.1055/s-2005-869979 |
© Georg Thieme Verlag Stuttgart · New York
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An Operationally Simple Base-Catalyzed Multi-component Domino Transformation: Stereoselective Preparation of Trisubstituted Alkenes and 1,3-Dienes
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| Hadjira Habib-Zahmania,b, Salih Hacinib, Cédric Boriesa, Robert Faurea, Jean Rodriguez*a |
a Université Paul Cézanne (Aix-Marseille III) , UMR-CNRS-6178-SymBio, Equipe RéSo, Réactivité en Synthèse organique, Centre de St Jérôme, boîte D12, 13397 Marseille cedex 20, France
Fax: +33(491)288861; e-Mail: jean.rodriguez@univ.u-3mrs.fr;
b Laboratoire de Synthèse Organique, Département de Chimie, Faculté des sciences, Université d'Oran-Es-Sénia, BP-1524, 31000 Oran, Algeria
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Received
3 February 2005 |
Abstract
A versatile and operationally simple base-catalyzed multi-component domino reaction between α,β-unsaturated carbonyl compounds, aldehydes, and alcohols is described, providing a new efficient, and stereoselective one-pot preparation of trisubstituted alkenes and 1,3-dienes. Key words
multi-component domino reaction - one-pot synthesis - trisubstituted alkenes - 1,3-dienes
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