PAPER	Synthesis 2005: 2487-2490   DOI: 10.1055/s-2005-872085
© Georg Thieme Verlag Stuttgart · New York
Carboxylic Acids from Primary Alcohols and Aldehydes by a Pyridinium Chlorochromate Catalyzed Oxidation
Mo Hunsen*
Department of Chemistry, Kenyon College, Gambier, OH 43022, USA Fax: +1(740)4275731; e-Mail: hunsenm@kenyon.edu.;
Received 8 February 2005

Abstract

A facile and quantitative preparation of carboxylic acids by a pyridinium chlorochromate (PCC) catalyzed (2 mol%) oxidation of primary alcohols and aldehydes using 2.2 equivalents and 1.1 equivalents of H₅IO₆, respectively, in acetonitrile is described here.

Key words

alcohols - aldehydes - oxidation - carboxylic acids - catalysis - pyridinium chlorochromate (PCC) - periodic acid