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PAPERSynthesis 2005: 2838-2844  
DOI: 10.1055/s-2005-872178

© Georg Thieme Verlag Stuttgart · New York

 

Rapid and Solvent-Free Synthesis of Homoallyl or Homopropargyl Alcohols Mediated by Zinc Powder
 
Jin-xian Wang*a,b, Xuefeng Jiaa, Tuanjie Menga, Li Xina
a Institute of Chemistry, Department of Chemistry, Northwest Normal University, 967 An Ning Road (E.), Lanzhou 730070, P. R. China
Fax: +86(931)7768159; e-Mail: Wangjx@nwnu.edu.cn;
b State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China
Received 20 April 2005

Abstract

A rapid and efficient procedure for the solvent-free synthesis of homoallylic and homopropargyl alcohols has been achieved by zinc-mediated Barbier-type reaction of carbonyl compounds at room temperature.

Key words

zinc powder - solvent-free - homoallylic alcohol - homopropargyl alcohol - carbonyl compounds

 
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