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| PAPER | Synthesis 2005: 2838-2844 DOI: 10.1055/s-2005-872178 |
© Georg Thieme Verlag Stuttgart · New York
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Rapid and Solvent-Free Synthesis of Homoallyl or Homopropargyl Alcohols Mediated by Zinc Powder
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| Jin-xian Wang*a,b, Xuefeng Jiaa, Tuanjie Menga, Li Xina |
a Institute of Chemistry, Department of Chemistry, Northwest Normal University, 967 An Ning Road (E.), Lanzhou 730070, P. R. China Fax: +86(931)7768159; e-Mail: Wangjx@nwnu.edu.cn; b State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China
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Received
20 April 2005 |
Abstract
A rapid and efficient procedure for the solvent-free synthesis of homoallylic and homopropargyl alcohols has been achieved by zinc-mediated Barbier-type reaction of carbonyl compounds at room temperature. Key words
zinc powder - solvent-free - homoallylic alcohol - homopropargyl alcohol - carbonyl compounds
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