PAPER	Synthesis 2005: 2897-2900   DOI: 10.1055/s-2005-918422
© Georg Thieme Verlag Stuttgart · New York
Carbon Tetrabromide: An Efficient Catalyst for Regioselective Ring Opening of Epoxides with Alcohols and Water
J. S. Yadav*, B. V. S. Reddy, K. Harikishan, Ch. Madan, A. V. Narsaiah
Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad-500 007, India Fax: +91(40)27160512; e-Mail: yadavpub@iict.res.in;
Received 6 December 2004

Abstract

Epoxides undergo rapid ring opening with a range of alcohols in the presence of catalytic amount of carbon tetrabromide under mild and convenient conditions to afford the corresponding β-alkoxy alcohols and 1,2-diols in high yields with high regioselectivity.

Keywords

epoxides - carbon tetrabromide - alcohols - β-hydroxy ethers