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| LETTER | Synlett 2005: 3109-3110
DOI: 10.1055/s-2005-921911 |
© Georg Thieme Verlag Stuttgart · New York
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Synthetic Studies on Poison-Frog Alkaloid 261C
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| Naoki Toyooka*a, Masashi Kawasakib, Hideo Nemoto*a, Suresh Awalec, Yasuhiro Tezukac, Shigetoshi Kadotac |
a Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Sugitani 2630, Toyama 930-0194, Japan
e-Mail: toyooka@ms.toyama-mpu.ac.jp;
b Department of Liberal Arts and Sciences, Faculty of Engineering, Toyama Prefectural University, Kurokawa 5180, Kosugi-Machi, Toyaama 939-0398, Japan
c Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, Sugitani 2630, Toyama 930-0194, Japan
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Received
22 September 2005 |
Abstract
The synthesis of highly substituted indolizidine core for the synthesis of poison-frog alkaloid 261C has been achieved. Key words
poison-frog alkaloid 261C - Mantella betsileo - 6,5,5-tricyclic ring system - α7 nicotinic acetylcholine receptors - highly substituted indolizidine core
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