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| PAPER | Synthesis 2006: 1480-1484
DOI: 10.1055/s-2006-926431 |
© Georg Thieme Verlag Stuttgart · New York
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Silicasulfuric Acid/NaNO3 as a New Reagent for the Deprotection of S,S-Acetals under Mild Conditions
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| Abdol R. Hajipour*a,b, Amin Zareia, Leila Khazdooza, Arnold E. Ruohob |
a Pharmaceutical Research Laboratory, College of Chemistry, Isfahan University of Technology, Isfahan 84156, Iran
b Department of Pharmacology, University of Wisconsin Medical School, 1300 University Avenue, Madison, WI 53706-1533, USA
e-Mail: haji@cc.iut.ac.ir;
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Received
9 January 2005 |
Abstract
An efficient, mild and chemoselective method for the deprotection of S,S-acetal compounds to their corresponding carbonyl compounds using silicasulfuric acid/NaNO3 is reported. Key word
silicasulfuric acid - sodium nitrate - deprotection - S,S-acetal
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