LETTER	Synlett 2006: 869-872   DOI: 10.1055/s-2006-939058
© Georg Thieme Verlag Stuttgart · New York
A New Synthesis of Aldehydes by the Palladium-Catalyzed Reaction of 2-Pyridinyl Esters with Hydrosilanes
Jun Nakanishi, Hiroto Tatamidani, Yoshiya Fukumoto, Naoto Chatani*
Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan Fax: +81(6)68797396; e-Mail: chatani@chem.eng.osaka-u.ac.jp;
Received 28 January 2006

Abstract

A new synthesis of aldehydes by the palladium-catalyzed reaction of 2-pyridinyl esters with hydrosilanes is described. The reaction is applicable to the preparation of aliphatic, aromatic, and α,β-unsaturated aldehydes. Various functional groups, such as fluoro, methoxy, aldehyde, acetal, and ester, are tolerated.

Key words

catalysis - 2-pyridinyl esters - hydrosilanes - aldehydes - palladium