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| LETTER | Synlett 2006: 1539-1542
DOI: 10.1055/s-2006-941606 |
© Georg Thieme Verlag Stuttgart · New York
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Revisiting the Passerini Reaction under Eco-Friendly Reaction Conditions
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| Carlos Kleber Z. Andrade*a, Sayuri Cristina S. Takadaa, Paulo Anselmo Z. Suarezb, Melquizedeque B. Alvesb |
a Laboratório de Química Metodológica e Orgânica Sintética (LaQMOS), Instituto de Química, Universidade de Brasília, C.P. 4478, 70910-970, Brasília, DF, Brazil
Fax: +55(61)32734149; e-Mail: ckleber@unb.br;
b Laboratório de Processamento de Recursos Naturais (LAPREN), Instituto de Química, Universidade de Brasília, C.P. 4478, 70910-970, Brasília, DF, Brazil
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Received
24 February 2006 |
Abstract
α-Acyloxy carboxamides were easily assessed in one step by the multicomponent reaction between carboxylic acids, aldehydes and C-isocyanides (Passerini reaction) using ionic liquids or polyethyleneglycol (PEG 400) as green reaction media. Key words
Passerini reaction - ionic liquids - polyethylene glycol - green chemistry
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