LETTER	Synlett 2006: 2246-2250   DOI: 10.1055/s-2006-949623
© Georg Thieme Verlag Stuttgart · New York
Cellulose-Supported Copper(0) Catalyst for Aza-Michael Addition
K. Rajender Reddy*, Nadakudity S. Kumar
Inorganic and Physical Chemistry Division, Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500 007, India Fax: +91(40)27160921; e-Mail: rajender@iict.res.in;
Received 2 March 2006

Abstract

Cellulose-supported copper(0) efficiently catalyzes the aza-Michael reaction of N-nucleophiles, such as amines and imidazoles with α,β-unsaturated compounds to produce the corresponding β-amino compounds and N-substituted imidazoles in excellent yields. The reactions are facile and the recovered catalyst is used for several cycles with consistent activity.

Key words

cellulose - copper - aza-Michael - amines - imidazoles - α,β-unsaturated compounds - β-amino compounds - N-substituted imidazoles