PAPER	Synthesis 2006: 3825-3830   DOI: 10.1055/s-2006-950296
© Georg Thieme Verlag Stuttgart · New York
Efficient and Rapid Friedlander Synthesis of Functionalized Quinolines Catalyzed by Neodymium(III) Nitrate Hexahydrate
Ravi Varala, Ramu Enugala, Srinivas R. Adapa*
Indian Institute of Chemical Technology, Hyderabad 500007, India Fax: +91(40)27160921; e-Mail: rvarala_iict@yahoo.co.in;
Received 26 June 2006

Abstract

Friedlander synthesis of quinolines catalyzed by neodymium nitrate [Nd(NO₃)₃·6H₂O, 5 mol%] in ethanol at room temperature was achieved in moderate to excellent yields (62-94%).

Key words

2-aminophenyl ketones - neodymium(III) nitrate - quinolines - annulations - domino reactions