PAPER	Synthesis 2007: 85-91   DOI: 10.1055/s-2006-950363
© Georg Thieme Verlag Stuttgart · New York
Sulfite-Promoted One-Pot Synthesis of Sulfides by Reaction of Aryl Disulfides with Alkyl Halides
Ri-yuan Tang, Ping Zhong*, Qiu-lian Lin
The School of Chemistry and Material Science, Wenzhou University, Wenzhou, P. R. of China Fax: +86(577)88373013; e-Mail: zhongp0512@163.com;
Received 9 August 2006

Abstract

A sodium dithionite, sodium thiosulfate and rongalite promoted one-pot synthesis of aryl alkyl sulfides at room temperature has been developed. The reactions of a range of disulfides with alkyl halides proceeded smoothly in the presence of rongalite. Possible reaction pathways are discussed and the effects of these sulfites on disulfides are investigated. The important features of this protocol are metal-free, strong-base-free, and mild reaction conditions, operational simplicity, short reaction times and high yields of products.

Key words

disulfide - sulfide - rongalite - electron transfer - one-pot reaction