PAPER	Synthesis 2007: 1165-1168   DOI: 10.1055/s-2007-965984
© Georg Thieme Verlag Stuttgart · New York
An Efficient Method for the α-Acetoxylation of Ketones
Jinmei Sheng, Xiaolong Li, Mingfang Tang, Botao Gao, Guosheng Huang*
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. of China Fax: +86(931)8912582; e-Mail: hgs2368@163.com;
Received 29 November 2006

Abstract

α-Acetoxylation of ketones catalyzed by iodobenzene using 30% aqueous hydrogen peroxide and acetic anhydride as the oxidant is an effective and economical method for the preparation of α-acetoxy ketones. The reaction gave the products in good yields without the addition of acetic acid and water.

Key words

acetoxylation - iodobenzene - α-acetoxy ketones - iodine(III) catalysts - oxidation