LETTER	Synlett 2007: 0243-0246   DOI: 10.1055/s-2007-968010
© Georg Thieme Verlag Stuttgart · New York
N,N-Dimethylglycine-Promoted Ullmann-Type Coupling Reactions of Aryl Iodides with Aliphatic Alcohols
Hui Zhang*a, Dawei Maa,b, Weiguo Caoa
a Department of Chemistry, Shanghai University, 99 Shangda Lu, Shanghai 200444, P. R. of China b State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, P. R. of China e-Mail: yehao7171@shu.edu.cn;
Received 17 August 2006

Abstract

The Ullmann-type coupling reactions of aryl iodides and aliphatic alcohols occur at 110 °C with N,N-dimethylglycine as the ligand, giving aryl alkyl ethers in good to excellent yields.

Key words

cross-coupling - aliphatic alcohols - catalysis - ligands - aryl iodides