LETTER	Synlett 2007: 0980-0982   DOI: 10.1055/s-2007-970784
© Georg Thieme Verlag Stuttgart · New York
Iodine-Magnesium Exchange on Unprotected Imidazoles in the Presence of LiCl
Felix Kopp, Paul Knochel*
Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, Haus F, 81377 München, Germany Fax: +49(89)218077680; e-Mail: Paul.Knochel@cup.uni-muenchen.de;
Received 28 December 2006

Abstract

The presence of LiCl allows the convenient preparation of magnesiated imidazoles starting from unprotected iodoimid­azoles. They react with various electrophiles in satisfactory yields.

Key words

magnesium - heterocycles - organometallic reagents - imidazole - exchange reaction