Klin Monbl Augenheilkd 2020; 237(06): 761-771
DOI: 10.1055/a-1114-1887
Übersicht

Hornhautveränderungen im Säuglings- und Kindesalter als Ausdruck systemischer Stoffwechselerkrankungen

Corneal Changes in Infancy and Childhood as an Expression of Systemic Metabolic Diseases
Michael Reich
1   Klinik für Augenheilkunde, Universitätsklinikum Freiburg
2   Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg
,
Thomas Reinhard
1   Klinik für Augenheilkunde, Universitätsklinikum Freiburg
2   Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg
,
Wolf Alexander Lagrèze
1   Klinik für Augenheilkunde, Universitätsklinikum Freiburg
2   Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg
› Institutsangaben

Zusammenfassung

Bilaterale Hornhauttrübungen können Ausdruck unterschiedlichster Systemerkrankungen sein. Insbesondere im Kindesalter ist hierbei differenzialdiagnostisch an diverse, aber meist sehr seltene Stoffwechselerkrankungen zu denken. Da die Hornhauttrübungen zu den ersten klinischen Symptomen dieser Erkrankungen zählen können, kommt dem Ophthalmologen eine entscheidende Rolle hinsichtlich der Einleitung einer frühen interdisziplinären diagnostischen Abklärung zu. Die frühe Diagnosestellung ist durch die daraus ggf. resultierende Therapieeinleitung für den weiteren klinischen Verlauf und die Prognose der betroffenen Patienten äußerst entscheidend.

Abstract

Bilateral corneal opacities can be a leading symptom of different systemic diseases. Especially in childhood, various metabolic diseases, although very rare, should be considered as a possible diagnosis. Since corneal opacities can be among the first clinical symptoms of these diseases, the ophthalmologist plays a central role in initiating early interdisciplinary diagnostics. The early diagnosis is extremely important for further prognosis and the clinical outcome of the affected patients due to the early initiation of therapy.



Publikationsverlauf

Eingereicht: 27. Januar 2020

Angenommen: 14. Februar 2020

Artikel online veröffentlicht:
09. April 2020

Georg Thieme Verlag KG
Stuttgart · New York

 
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