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Thromb Haemost 1999; 81(04): 647-656
DOI: 10.1055/s-0037-1614540
Scientific and Standardization Committee Communication
Schattauer GmbH

Inventory of Exogenous Hemostatic Factors Derived from Arthropods

On behalf of the Registry of Exogenous Hemostatic Factors of the Scientific and Standardization Subcommittee of the International Society on Thrombosis and Haemostasis; Registry Chairman: Neville Marsh
C. L. Arocha-Piñango
1   From the Instituto Venezolano de Investigaciones Científicas (IVIC), Centro de Medicina Experimental, Caracas, Venezuela
,
R. Marchi
1   From the Instituto Venezolano de Investigaciones Científicas (IVIC), Centro de Medicina Experimental, Caracas, Venezuela
,
B. Guerrero
1   From the Instituto Venezolano de Investigaciones Científicas (IVIC), Centro de Medicina Experimental, Caracas, Venezuela
› Author Affiliations
Further Information

Publication History

Received 30 November 1998

Accepted 08 January 1999

Publication Date:
09 December 2017 (online)

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Summary

In many arthropods agents have been detected which affect the hemostatic mechanism. Some agents, such as those identified in hematophagus arthropods, seem to have evolved to help the animal in the feeding process while, in others, the function cannot be explained, but may be part of a defense mechanism (see Refs. 1-3).

Some arthropods possess several agents while in others one agent has different activities, i.e., antithrombin activity as well as inhibition of platelet aggregation. Many agents have been only partially characterized while others have been cloned and prepared in recombinant form.The majority of the agents are small proteins. As to the nomenclature, some agents have been described by the authors but have not been assigned proper names.

 

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