Thromb Haemost 1986; 55(03): 388-389
DOI: 10.1055/s-0038-1661570
Original Article
Schattauer GmbH Stuttgart

Inhibition of Tissue-Type Plasminogen Activator in Plasma of Women Using Oral Contraceptives and in Normal Women During a Menstrual Cycle

J Jespersen
The Section of Coagulation and Fibrinolysis, Department of Clinical Chemistry, Ribe County Flospital in Esbjerg, and Section for Thrombosis Research, South Jutland University Centre, Esbjerg, Denmark
,
C Kluft
*   The TNO Gaubius Institute for Cardiovascular Research, Leiden, The Netherlands
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received 02. Februar 1986

Accepted 17. April 1986

Publikationsdatum:
18. Juli 2018 (online)

Summary

Tissue-type plasminogen activator (t-PA) inhibition in plasma was assessed in 15 normal women and in 10 women using oral contraceptives (OC) containing 30 μg ethinyl oestradiol and 150 μg levo-norgestrel. The levels of t-PA inhibition were significantly lower in the OC group with marked fluctuations related to the hormone cycle. Normal women had only minor fluctuations.

 
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