RENAL ARTERY REMODELING IN PATIENTS WITH CARDIOVASCULAR PATHOLOGY

Purpose: The aim of this investigation was to study characteristics of renal artery remodeling in patients with hypertension and ischemic heart disease.

Methods and Materials: The population of this study consisted of 143 patients (males and females, aged from 16 to 80 years) with hypertension (79 patients; group 1), ischemic heart disease (21 patients; group 2) and 44 healthy persons (group 3). An ALOKA SSD 4000 ultrasound imaging system was used in this study. Examination was performed with convex 2–6MHz transducer. The main renal artery path, peak systolic, end diastolic velocities in main, segmental, interlobar, arcuate, interlobular renal arteries, RI, PI, S/D ratio and also maximal main renal vein velocity were derived from two-dimensional echography with harmonic echo, color and pulse-waved Doppler.

Results: Results are demonstrated in the table.As we see from the table, patients with ischemic heart disease have the same abnormalities of renal vasculature as patients with hypertension: increased resistance of renal arteries flow, venous hypertension and impoverishment of renal vascular pattern, kinking and stenosis of the main renal artery.

Table:

Results	Group 1	Group 2	Group 3
Normal vascularpattern	24.0	19.0	88.7
Congenitalmalformations	8.9	5.0	9.0
Increasedresistance	16.5	33.0	0
Venoushypertension	20.3	19.0	0
Impoverishmentof vasculature	8.9	5.0	0
S-kinking ofmain renal arter	11.4	15.0	2.3
Stenosis ofrenal artery	40.6	25.0	0
1 group vs. 2 p>.05, 1 and 2 groups vs. 3 p<.05

Conclusions: Remodeling of renal arteries can develop in patients with ischemic heart disease with normal blood pressure level. Ischemic heart disease changes renal artery wall, its path, velocity of blood flow like arterial hypertension.