CC BY-NC-ND 4.0 · South Asian J Cancer 2014; 03(04): 223-226
DOI: 10.4103/2278-330X.142984
URO-ONCOLOGY : Original Article

Urodynamic and continence assessment of orthotropic neobladder reconstruction following radical cystectomy in bladder cancer; a prospective, blinded North Indian tertiary care experience

Vishwajeet Singh
Department of Urology, King George’s Medical University (erstwhile Chattrapati Shahuji Maharaj Medical University), Lucknow, Uttar Pradesh, India
,
Swarnendu Mandal
Department of Urology, King George’s Medical University (erstwhile Chattrapati Shahuji Maharaj Medical University), Lucknow, Uttar Pradesh, India
,
Sachin Patil
Department of Urology, King George’s Medical University (erstwhile Chattrapati Shahuji Maharaj Medical University), Lucknow, Uttar Pradesh, India
,
Rahul Janak Sinha
Department of Urology, King George’s Medical University (erstwhile Chattrapati Shahuji Maharaj Medical University), Lucknow, Uttar Pradesh, India
,
Dheeraj Kumar Gupta
Department of Urology, King George’s Medical University (erstwhile Chattrapati Shahuji Maharaj Medical University), Lucknow, Uttar Pradesh, India
,
Satya Narayan Sankhwar
Department of Urology, King George’s Medical University (erstwhile Chattrapati Shahuji Maharaj Medical University), Lucknow, Uttar Pradesh, India
› Author Affiliations
Source of Support: Nill.

Abstract

Aim: The aim of this study is to compare urodynamic and continence parameters among patients undergoing orthotropic neo-bladder substitution with sigmoid or ileal segments. Variations in the Urodynamic parameter between the continent and incontinent patients were also evaluated. Patients and Methods: From January 2008 to March 2012, 44 patients underwent ileal neobladder (IN) reconstruction and 36 patients underwent sigmoid neobladder (SN) reconstruction. Evaluation of Urodynamic and Continence parameters was performed at 12 months after surgery. Results: The average capacity of IN and SN was 510 ml and 532 ml respectively. The voiding pressure, mean peak flow rates and post void residual urine (PVRU) for IN and SN were 27.5 cm H 2 O versus 37 cm H 2 O, 15ml/s versus 17ml/s and 36 ml versus 25 ml respectively. Daytime continence for IN and SN was 93% (41/44) and 89% (32/36), and night-time continence was 91% (40/44) and 78% (28/36) respectively. The compliance, maximum cystometric capacity and PVRU in the daytime continent (versus incontinent) were 61 (versus 41), 471 (versus 651) and 22 (versus 124) and in the night-time continent (versus incontinent) were 57 (versus 43), 437 (versus 654) and 18 (versus 105) respectively. Conclusion: A neobladder constructed from detubularized ileum or sigmoid achieves urodynamically proven adequate capacity and compliance with 89-93% daytime and 78-91% night time continence. Continent men when compared with incontinent (both daytime and night time) were more likely to have comparatively higher compliance, lower maximum cystometric capacity and lower PVRU. Urodynamic study could predict which incontinent men would improve with pelvic floor exercises and clean intermittent catheterization (CIC).



Publication History

Article published online:
31 December 2020

© 2014. MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. https://creativecommons.org/licenses/by-nc-nd/4.0/.

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Hautmann RE, Abol-Enein H, Hafez K, Haro I, Mansson W, Mills RD, et al. World Health Organization (WHO) consensus conference on bladder cancer: Urinary diversion. Urology 2007; 69:17-49.
  • 2 Thüroff JW, Mattiasson A, Andersen JT, Hedlund H, Hinman F Jr, Hohenfellner M, et al. The standardization of terminology and assessment of functional characteristics of intestinal urinary reservoirs. BJU Int. 1996;78:516-23.
  • 3 Fujisawa M, Isotani S, Gotoh A, Hara I, Okada H, Arakawa S, et al.: Voiding dysfunction of sigmoid neobladder in women: A comparative study with men. Eur Urol 2001;40:191-5.
  • 4 Berglund B, Kock NG. Volume capacity and pressure characteristics of various types of intestinal reservoirs. World J Surg. 1987;11:798-803.
  • 5 Parekh DJ, Gilbert WB, and Smith JA Jr. Functional lower urinary tract voiding outcomes after cystectomy and orthotopic neobladder. J Urol 2000;163:56-9.
  • 6 Schrier BP, Laguna MP, van der Pal F, Isorna S, Witjes JA.: Comparison of orthotopic sigmoid and ileal neobladders: Continence and urodynamic parameters. Eur Urol 2005;47:679-85.
  • 7 Koraitim MM, Atta MA, Foda MK. Orthotopic Bladder Substitution in Men Revisited: Identification of Continence Predictors. J Urol 2006;176:2081-84.
  • 8 Shimogaki H, Okada H, Fujisawa M, Arakawa S, Kawabata G, Kamidono S, et al.: Long-term experience with orthotopic reconstruction of the lower urinary tract in women. J Urol 1999;161:573-7.
  • 9 Kato M, Takeda A, Saito S, Terai A, Taki Y, Kato S, et al. Long-Term Functional Outcomes of Ileal and Sigmoid Orthotopic Neobladder Procedures. Urology 2007;69:74-7.
  • 10 Chen Z, Lu G, Li X, Li X, Fang Q, Ji H, et al. Better Compliance Contributes to Better Nocturnal Continence With Orthotopic Ileal Neobladder Than Ileocolonic Neobladder After Radical Cystectomy for Bladder Cancer. Urology 2009;73:838-44.
  • 11 Porru D, Dore A, Usai M, Campus G, Delisa A, Scarpa RM, et al. Behavior and urodynamic properties of orthotopic ileal bladder substitute after radical cystectomy. Urol Int 1994;53:30-3.
  • 12 El Bahnasawy MS, Osman Y, Gomha MA, Shaaban AA. Persistent and occasional nocturnal enuresis in orthotopic urinary diversion: Is there a urodynamic difference?. BJU Int 2005;96:1373-7.
  • 13 Broderick GA, Narayan P, Tanagho EA. The dynamics of continence in the detubularized ileocecal reservoir. J Urol1989;141:304A
  • 14 Marshall FF, Mostwin JL, Radebough LC, Walsh PC, Brendler CB. Ileocolic neobladder, Post-cystectomy continence and potency. J Urol 1991;145:502-4.
  • 15 Burkhard FC, Kessler TM, Springer J, Studer UE. Early and late urodynamic assessment of ileal orthotopic bladder substitutes combined with an afferent tubular segment. J Urol 2006;175:2155-61.