Management of Borderline Ovarian Tumors (BOT): results of a retrospective, single center study in Switzerland

Background Borderline tumors are malignant epithelial ovarian tumors with a very low incidence. Thus experience in diagnostics and treatment is still rare. The aim of this study was to present and analyze data of women with borderline ovarian tumor (BOT) regarding clinical features, histological characteristics, diagnostics and treatment management.

Methods In this single center retrospective study women with BOT treated at the Departement of Gynecology and Obstetrics at the Kantonsspital Luzern between 2011 and 2018 were analyzed according to their clinical and histological reports.

Results A total of 42 women were enrolled. The median age was 58,5 with a range from 26 to 85, of which 31(73,81%) were postmenopausal, and 11 (26,19%) were still menstruating.

Regarding the histological subtypes, 23 women (54,76%) had serous and 15 (35,71%) had mucinous BOT. Seromucinous histology was found in 3 patients (7,14%) and endometrioid in 1 woman (2,38%) respectively. All women underwent surgery. In a total of 39 women (92,86%) a complete surgical staging for BOT was performed. In 29 women (69,05%) staging was performed by laparoscopy, 13 (30,95%) underwent laparotomy. Only 1 patient (2,38%) received chemotherapy.

The mean follow up was 52 months (range=16.3-101.4 months). During this period two patients recurred after 21,7 and 44 months respectively, the second woman died after 53 months because of the BOT.

Conclusion In the present study women were treated according to the international therapy recommendations and the rate of recurrence was very low.

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Publication History

Article published online:
07 October 2020