Z Gastroenterol 2021; 59(08): e355-e356
DOI: 10.1055/s-0041-1734300
POSTER
Hepatologie

Epidemiological trends of Hepatobiliary Carcinomas in Austria 2009-2018 - an update

F Hucke
1   Klinikum Klagenfurt - Abtl. für Gastroenterologie u. Hepatologie, Endokrinologie, Rheumatologie und Nephrologie, Klagenfurt, Austria
,
M Pinter
2   Universitätsklinik für Innere Medizin III - Abtl. für Gastroenterologie/Hepatologie - AKH& Medizinische Universität Wien, Wien, Austria
,
D Bolf
1   Klinikum Klagenfurt - Abtl. für Gastroenterologie u. Hepatologie, Endokrinologie, Rheumatologie und Nephrologie, Klagenfurt, Austria
,
S Bota
1   Klinikum Klagenfurt - Abtl. für Gastroenterologie u. Hepatologie, Endokrinologie, Rheumatologie und Nephrologie, Klagenfurt, Austria
,
M Peck-Radosavljevic
1   Klinikum Klagenfurt - Abtl. für Gastroenterologie u. Hepatologie, Endokrinologie, Rheumatologie und Nephrologie, Klagenfurt, Austria
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    Background In 2014 we analysed epidemiological trends of hepatobiliary carcinomas (HBC) in Austria from 1990-2009. Now we investigated the further trends from 2009-2018.

    Methods Patients diagnosed with hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (iCCC), extrahepatic cholangiocarcinoma (eCCC), gallbladder carcinoma (GBC) and ampullary carcinoma(AC) were included. Data on age-adjusted incidence rates were obtained from the Austrian National Cancer Registry. Data on age-adjusted mortality rates were obtained from the national death registry (Statistik Austria).

    Results Between 2009 and 2018, 14291 patients were diagnosed with HBC (7930 HCC, 2064 iCCC, 1812 eCCC, 1543 GBC, 612 AC). The median overall survival (OS) of all patients was 7.1 months (1/5 year OS: 40 %/8 %), with the best OS in patients with AC (25.1 months) and worst in patients with ICC (4.9 months). Lymphnode or distant metastases were associated with poorer survival and most frequent in GBC and iCCC. Overall survival significantly improved in HCC, ECC, GC, AC compared to 1990-2009. In HCC the incidence rates decreased in both men and women, the mortality rates slightly decreased in men and remained stable in women. In iCCC, incidences remained stable in both sexes, while mortality increased in men and decreased in women. In eCCC, the age-adjusted incidence rates increased in men and decreased in women, the mortality rates increased in men and remained stable women. In GBC the incidence and mortality rates decreased in both sexes. In AC, the incidences decreased in women and remained stable in men, the mortality rates decreased in both sexes.

    Conclucion Age-adjusted incidence and mortality rates decreased in HCC, GBC and partly in AC. While incidences and mortality of eCCC/iCCC rather increased in men, those remained stable or decreased in women. Overall survival improved in almost all entities compared to 1990-2009.


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    Artikel online veröffentlicht:
    01. September 2021

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