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Semin Respir Crit Care Med 2016; 37(02): 257-266
DOI: 10.1055/s-0036-1578802
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Fungal, Viral, and Parasitic Pneumonias Associated with Human Immunodeficiency Virus

Joseph H. Skalski
1   Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota
,
Andrew H. Limper
1   Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota
› Author Affiliations
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Publication History

Publication Date:
14 March 2016 (online)

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Abstract

Respiratory illness is an important cause of morbidity and mortality in patients with human immunodeficiency virus (HIV). The spectrum of pulmonary disease that can affect patients with HIV is wide and includes opportunistic infection with many fungal, viral, and parasitic organisms. This article reviews the clinical presentation; approach to diagnosis; and management of fungal, viral, and parasitic pneumonias that can develop in patients with HIV including respiratory disease caused by Aspergillus, Cryptococcus, Histoplasma, Coccidioides, Cytomegalovirus, Toxoplasma, and Strongyloides. Because clinical symptoms and radiographic patterns are often insensitive at distinguishing these pulmonary infections, this review particularly focuses on specific host risk factors and diagnostic testing to consider when approaching HIV patients with respiratory illness.

Keywords

opportunistic infection - acquired immunodeficiency syndrome - aspergillosis - Cryptococcus - histoplasmosis - coccidioidomycosis - cytomegalovirus - Strongyloides - toxoplasmosis