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Semin Respir Crit Care Med 2016; 37(03): 406-420
DOI: 10.1055/s-0036-1580691
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Lymphoid Interstitial Pneumonia and Other Benign Lymphoid Disorders

Antonella Arcadu
1   Department of Respiratory Disease, University of Sassari, Sassari, Italy
,
Teng Moua
2   Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota
,
Eunhee S. Yi
3   Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota
,
Jay H. Ryu
2   Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota
› Author Affiliations
Further Information

Publication History

Publication Date:
27 May 2016 (online)

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Abstract

Benign pulmonary lymphoid disorders include a variety of rare lymphoid abnormalities characterized by a polyclonal lymphoid infiltrate with differing histopathologic patterns and clinicoradiologic features that may overlap. Histological examination is essential to reach a correct diagnosis and to exclude alternative causes, although this task can at times prove difficult. Further studies and clinical trials are needed to provide additional insights on pathogenesis and to guide the therapeutic management of these disorders. The purpose of this article is to review the histopathological, epidemiological, and clinicoradiologic features of several benign pulmonary lymphoid disorders, including lymphoid interstitial pneumonia, follicular bronchiolitis, nodular lymphoid hyperplasia (pulmonary pseudolymphoma), inflammatory pseudotumor, immunoglobulin G4-related disease, Castleman disease, posttransplantation lymphoproliferative disease, and drug-induced lymphoid disorders.

Keywords

lymphoid interstitial pneumonia - pulmonary lymphoid disorders - pseudolymphoma - Castleman disease
 

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