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Endoscopy 2005; 37(7): 630-634
DOI: 10.1055/s-2005-870127
Reviews: Update on Upper GI Submucosal Tumors
© Georg Thieme Verlag KG Stuttgart · New York

Histopathological Classification of Nonneoplastic and Neoplastic Gastrointestinal Submucosal Lesions

T.  Wiech1 , A.  Walch2 , M.  Werner1
  • 1Institute of Pathology, Freiburg University Hospital, Freiburg im Breisgau, Germany
  • 2Institute of Pathology, National Research Center for Environment and Health, Neuherberg, Munich, Germany
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Publication History

Publication Date:
11 July 2005 (online)

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This article provides an overview of the histopathologically defined nonneoplastic and neoplastic entities involved in submucosal lesions (SMLs) of the gastrointestinal tract, particularly those in the upper gastrointestinal tract. The gross appearance and the histomorphological and cytomorphological features of the most frequent SMLs are described, including gastrointestinal stromal tumor (GIST), leiomyoma, lipoma, carcinoid, granular-cell tumor, glomus tumor, schwannoma, submucosal metastases, Brunner’s gland hamartoma, pancreatic rests, and cysts. The current state of important technical aspects of biopsy processing and the role of histology and cytology in the diagnosis of SMLs are discussed.

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M. Werner, M. D.

Universitätsklinikum Freiburg · Pathologisches Institut

Albertstrasse 19 · 79002 Freiburg im Breisgau · Germany

Fax: +49-761-203 6818

Email: dirpath@mail1.uniklinik-freiburg.de

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