Pregabalin in Benzodiazepine Withdrawal

Introduction

Pregabalin is a well tolerated treatment for generalized and social anxiety (licensed only in European countries and not in the USA), epilepsy as well as neuropathic pain [2].

References

• 1 Bateson A. Further potential of the GABA receptor in the treatment of insomnia.  Sleep Medicine. 2007;  7 3-9
• 2 Montgomery SA. Pregabalin for the treatment of generalized anxiety disorder.  Expert Opin Pharmacother. 2006;  7 2139-2154
• 3 Rupprecht R, Eser D, Zwanzger P, Möller HJ. GABA-A receptors as targets for novel anxiolytic drugs.  World J Biol Psychiatry. 2006;  7 231-237
• 4 Taylor CP, Angelotti T, Fauman E. Pharmacology and mechanism of action of pregabalin: the calcium channel alpha2-delta (alpha2-delta) subunit as a target for antiepileptic drug discovery.  Epilepsy Res. 2007;  73 137-150
• 5 Victorri-Vigneau C, Guerlais M, Jolliet P. Abuse, dependency and withdrawal with gabapentin: a first case report.  Pharmacopsychiatry. 2007;  40 43-44
• 6 Zullino DF, Khazaal Y, Hattenschwiler J, Borgeat F, Besson J. Anticonvulsant drugs in the treatment of substance withdrawal.  Drugs Today (Barc). 2004;  40 603-619

Correspondence