The Activity of Heparin in the Presence and Absence of Ca2+ Ions; why the Anti-Xa Activity of LMW Heparins Is about two Times Overestimated

Thromb Haemost 1993; 70(04): 717-718
DOI: 10.1055/s-0038-1649656

Letter to the Editor

Schattauer GmbH Stuttgart

The Activity of Heparin in the Presence and Absence of Ca²⁺ Ions; why the Anti-Xa Activity of LMW Heparins Is about two Times Overestimated

H C Hemker

Department of Biochemistry, Cardiovascular Research Institute Maastricht and Medical Faculty Rijksuniversiteit Limburg, Maastricht, The Netherlands

,

S Béguin

Department of Biochemistry, Cardiovascular Research Institute Maastricht and Medical Faculty Rijksuniversiteit Limburg, Maastricht, The Netherlands

References
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5 Hemker HC, Béguin S, Bendetowicz AV, Wielders S. The determination of the levels of unfractionated and low molecular weight heparins in plasma. Their effect on thrombin mediated feedback reactions in vivo. Preliminary results on samples after subcutaneous injection. Haemostasis 1991; 21: 258-272
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