Fetal Thrombotic Vasculopathy

Lily Marsden; Jessica Comstock

doi:10.1007/s40556-015-0054-y

Journal of Fetal Medicine, Table of Contents

CC BY-NC-ND 4.0 · Journal of Fetal Medicine 2015; 02(03): 121-125
DOI: 10.1007/s40556-015-0054-y

Review Article

Fetal Thrombotic Vasculopathy

Lily Marsden

¹Division of Pediatric Pathology, Department of Pathology, Primary Children’s Hospital, University of Utah, 100 N. Mario Capecchi Dr., 84113, Salt Lake City, UT, USA

,

Jessica Comstock

¹Division of Pediatric Pathology, Department of Pathology, Primary Children’s Hospital, University of Utah, 100 N. Mario Capecchi Dr., 84113, Salt Lake City, UT, USA

› Author Affiliations

Abstract

PDF Download

Abstract

Fetal thrombotic vasculopathy (FTV) is the term used to encompass the histologic findings identified in placentas with fetal thrombotic lesions: occlusive and nonocclusive chorionic vessel thrombi, avascular villi in the distribution of a single villous tree, intramural vascular fibrin, and hemorrhagic endovasculitis. The underlying etiology of FTV is largely unknown though hypercoagulability and circulatory stasis have been the main focuses in the literature to explain the hemostatic abnormalities. This article reviews the literature in both defining and discussing, potential etiologies of FTV, as well as neonatal outcomes.

Keywords

Fetal thrombotic vasculopathy - Thrombophilia - Thrombosis - Avascular villi - Cerebral palsy

PDF (949 kb)