Role of Predictive Mortality Calculator in Antenatal Assessment of Congenital Diaphragmatic Hernia

Azril Ishak; Hasyma Abu Hassan; Amilia Afzan Mohd Jamil; Vairavan Ramesh

doi:10.1007/s40556-021-00315-5

Journal of Fetal Medicine, Table of Contents

CC BY-NC-ND 4.0 · Journal of Fetal Medicine 2021; 08(03): 211-215
DOI: 10.1007/s40556-021-00315-5

Case Reports

Role of Predictive Mortality Calculator in Antenatal Assessment of Congenital Diaphragmatic Hernia

Authors

Azril Ishak

¹Department of Radiology, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia

²Department of Radiology, Hospital Serdang, Jalan Puchong, 43000, Kajang, Selangor, Malaysia
Hasyma Abu Hassan

¹Department of Radiology, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia
Amilia Afzan Mohd Jamil

³Department of Obstetrics and Gynaecology, Department of Radiology, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia
Vairavan Ramesh

⁴Department of Obstetrics and Gynaecology, Hospital Serdang, Jalan Puchong, 43000, Kajang, Selangor, Malaysia

Abstract

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Abstract

Congenital diaphragmatic hernia (CDH) is one of the most common major congenital anomalies. In utero visceral organ herniation into the thoracic cavity can result in lung hypoplasia and pulmonary hypertension may ensue. Post-natal mortality rates in isolated CDH remain high reaching up to 80% in severe cases. Several prenatal predictors of morbidity and mortality have been proposed. Reliable predictive markers can aid clinicians in providing effective family counselling, prediction of survival, and propose therapeutic options. Decreased total fetal lung volume (TFLV) via magnetic resonance imaging (MRI) has been reported to be significantly associated with mortality. We report on 2 cases of CDH, with fetal MRI performed at third trimester, focusing on the TFLV and observed-to-expected TFLV. We would like to highlight the importance of predictive mortality calculator which provides statistical data for healthcare providers in counselling families and aids in risk-stratification.

Keywords

Total fetal lung volume (TFLV) - Congenital diaphragmatic hernia - Fetal MRI

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