Ultraschall Med 2019; 40(04): 504-512
DOI: 10.1055/a-0651-0542
Original Article
© Georg Thieme Verlag KG Stuttgart · New York

Comparison of Liver Shear Wave Elastography Measurements using Siemens Acuson S3000, GE LOGIQ E9, Philips EPIQ7 and Toshiba Aplio 500 (Software Versions 5.0 and 6.0) in Healthy Volunteers

Vergleich der Scherwellen-Elastografie-Messung der Leber zwischen Siemens Acuson S3000, GE LOGIQ E9, Philips EPIQ7 and Toshiba Aplio 500 (Softwareversionen 5.0 und 6.0) an gesunden Probanden
Victoria Sofie Gress
Department of Internal Medicine I, University Hospital Ulm, Germany
,
Elisa Nadine Glawion
Department of Internal Medicine I, University Hospital Ulm, Germany
,
Julian Schmidberger
Department of Internal Medicine I, University Hospital Ulm, Germany
,
Wolfgang Kratzer
Department of Internal Medicine I, University Hospital Ulm, Germany
› Institutsangaben
Weitere Informationen

Publikationsverlauf

20. Dezember 2017

26. Juni 2018

Publikationsdatum:
23. Oktober 2018 (online)

Abstract

Aim To compare ARFI-based elastography procedures of the GE LOGIQ E9, Philips EPIQ7, and Toshiba Aplio 500 (versions 5.0 and 6.0) ultrasound scanners with the Siemens Acuson S3000 reference scanner in subjects with healthy livers, taking various impact factors into account.

Materials and Methods The study consisted of two subsequent study parts. Study 1 (n = 205) evaluated the 2D-SWE techniques of GE and Toshiba 5.0 and the pSWE technique of the Philips scanner against the reference scanner Siemens. Study 2 (n = 113) evaluated Toshiba 6.0 against Siemens in a different cohort. Out of 433 study participants in both studies, 318 (M:F = 122:196) met the inclusion criteria. Elastography measurements were performed in the right lobe of the liver at depths of 3, 5 and 7 cm. At each depth, five measurements were acquired with the Siemens and Philips scanners and one measurement each with the GE and Toshiba machines.

Results The Philips (r = 0.58, p < 0.0001) and the GE (r = 0.63, p < 0.0001) scanners showed the strongest correlation of shear wave velocities between Siemens and comparator scanners, at a depth of 5 cm. We found the strongest relationship with Toshiba (software version 6.0) at a depth of 3 cm (r = 0.57, p < 0.0001). Toshiba software version 5.0 did not give satisfactory results. The factors of sex and BMI showed scanner-specific differences in the values measured (p < 0.05). The age of the subjects did not seem to have any effect.

Conclusion With the exception of Toshiba software version 5.0, all of the scanners we tested can be recommended without reservation for comparative ultrasound elastography of the healthy liver at measurement depths of 3 cm up to 5 cm.

Zusammenfassung

Ziel Vergleich der ARFI-basierten Elastografie-Verfahren der Sonografie-Geräte GE LOGIQ E9, Philips EPIQ7 und Toshiba Aplio 500 (Softwareversion 5.0 und 6.0) mit dem Referenzgerät Siemens Acuson S3000 an Lebergesunden, unter Berücksichtigung verschiedener Einflussfaktoren.

Material und Methoden Die Studie bestand aus 2 Folgestudien: In der ersten Studie (n = 205) wurden die 2D-SWE-Geräte GE und Toshiba 5.0 sowie das pSWE-Gerät von Philips gegen das Siemens-Referenzgerät getestet. In einer zweiten Studie (n = 113) wurde an einem weiteren Kollektiv Toshiba 6.0 mit Siemens verglichen. Insgesamt erfüllten 318 (M:F = 122:196) von 433 Studienteilnehmern die Einschlusskriterien. Die Elastografie-Messungen wurden im rechten Leberlappen in 3, 5 und 7 cm Tiefe durchgeführt. Für Siemens und Philips wurden pro Tiefe je 5 Messungen, für GE und Toshiba jeweils 1 Messung durchgeführt.

Ergebnisse Die stärkste Korrelation der Scherwellengeschwindigkeiten zwischen Siemens und Vergleichsgeräten konnte für Philips (r = 0,58, p < 0,0001) und GE (r = 0,63, p < 0,0001) in 5 cm Messtiefe erfasst werden. Bei Toshiba (Softwareversion 6.0) fand sich die stärkste Korrelation in 3 cm Messtiefe (r = 0,57, p < 0,0001). Die Toshiba-Softwareversion 5.0 lieferte keine zufriedenstellenden Ergebnisse. Gerätespezifische Unterschiede der Messwerte zeigten sich für die Einflussfaktoren Geschlecht und BMI (p < 0,05). Das Alter der Probanden scheint keinen Einfluss zu haben.

Schlussfolgerung Alle untersuchten Geräte, mit Ausnahme der Toshiba-Softwareversion 5.0, können für die Messtiefen von 3 und 5 cm uneingeschränkt für vergleichende Ultraschall-Elastografie-Untersuchungen an Lebergesunden empfohlen werden.

 
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