 
         
         
         Gesundheitsbezogene Lebensqualität gewinnt als Zielparameter für verschiedene Akteure
            des Gesundheitswesens an Bedeutung, z. B. bei der Therapieevaluation von chronisch
            kranken 
            Patienten. In diesem Artikel beschreiben wir die unterschiedlichen Ebenen der „gesundheitsbezogenen
            Lebensqualität“, aktuelle Methoden zur Erfassung patientenberichteter
            Gesundheitsmerkmale sowie moderne testtheoretische Ansätze und deren Anwendungsmöglichkeiten.
         
         
         
            
Abstract
            
            Health-related quality of life (HRQoL) acquires increased importance as a target parameter
               for different stakeholders in healthcare, e. g. to assess treatment outcome in chronically
               ill patients. In this educational article, we explain the levels of the health-related
               quality of life construct and associated main dimensions including physical, mental
               and social health. State-of-the-art approaches for assessment of patient-reported
               outcomes (PROs) are introduced on the basis of the HRQoL model. Furthermore, modern
               test-theoretical approaches and their applications are presented, which are aimed
               at standardizing and improving the assessment of PROs (e. g., computer-adaptive testing).
               Finally, we present 2 major international PRO initiatives (PROMIS® and EORTC Quality of Life Group) that have been influential in advancing the assessment
               of patient outcomes over the last few years.
            
         
         Schlüsselwörter
patientenberichtete Gesundheitsmerkmale - gesundheitsbezogene Lebensqualität - probabilistische
            Testtheorie - Computer-adaptive Tests - Itembank
Key words
patient-reported outcomes - Health-related Quality of Life - Item-response theory
            - computer-adaptive testing - item bank