Soft Tissue Sarcoma – a Current Review of the Diagnostic and Treatment Strategies

Sebastian Scheidt; Cornelius Jacobs; Sebastian Koob; Kristian Welle; Sebastian Walter; Jens Jakob; Michael Kehrer; Jan Schmolders

doi:10.1055/a-0820-6366

Zeitschrift für Orthopädie und Unfallchirurgie, Table of Contents

Z Orthop Unfall 2019; 157(06): 644-653
DOI: 10.1055/a-0820-6366

Review/Übersicht

Georg Thieme Verlag KG Stuttgart · New York

Weichteilsarkome – eine Übersicht aktueller evidenzbasierter Behandlungskonzepte

Article in several languages: English | deutsch

Authors

Sebastian Scheidt

¹Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn
Cornelius Jacobs

¹Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn
Sebastian Koob

¹Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn
Kristian Welle

¹Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn
Sebastian Walter

¹Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn
Jens Jakob

²Universitätsmedizin Göttingen, Klinik für Allgemein-, Viszeral- und Kinderchirurgie
Michael Kehrer

¹Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn
Jan Schmolders

¹Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn

Abstract

Zusammenfassung

Weichteilsarkome sind eine heterogene Gruppe von seltenen Neoplasien, die aufgrund ihrer anatomischen Lage und ihres oft inapparenten klinischen Erscheinungsbildes eine häufig zu spät diagnostizierte Tumorentität darstellen. Gerade weichteilige Schwellungen werden initial oft fehlinterpretiert und im Gegensatz zu den gängigen Behandlungsleitlinien bagatellisiert oder inkorrekt biopsiert. Die daraus resultierenden Komplikationen sind für den Patienten gravierend und können durch Befolgen gewisser Behandlungsgrundsätze minimiert werden. Die Behandlung der Weichteilsarkome kann nur im interdisziplinären Kontext unter Einbeziehung von chirurgischen Fächern, Onkologie, Pathologie und Strahlentherapie gelingen und sollte beginnend mit der Biopsie an Tumorzentren durchgeführt werden. Dieser Übersichtsartikel versucht, anhand einer selektiven Literaturrecherche eine Übersicht über die aktuelle Evidenzlage zur Behandlung dieser Tumorentität aufzuzeigen und einen Behandlungsalgorithmus darzustellen.

Schlüsselwörter

Weichteilsarkom - Tumororthopädie - Behandlungsalgorithmus - Leitlinien - Übersichtsartikel

Full Text

References

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