Zusammenfassung
Die Kasuistik beschreibt den ersten dokumentierten Fall mit einer klinisch gesicherten
schweren Anaphylaxie nach Ticagrelor bei einem 76-jährigen männlichen Patienten mit
ST-Hebungs-Myokardinfarkt (STEMI).
Abstract
Background Ticagrelor as a P2Y12 receptor antagonist is recommended in patients with acute coronary
syndrome without a primary cardiosurgical therapy. Severe relevant side effects, especially
anaphylactic reactions, have not yet been described in the current literature.
Case presentation We describe the first documented case in the current literature with a severe anaphylaxis
after ticagrelor in a 76-year-old male patient with ST-elevation myocardial infarction.
The diagnosis seems to be objectivated by the observed time-related life-threatening
event after repetitive administration of ticagrelor and the rapid stabilization after
adequate anaphylactic treatment.
Conclusion This case should raise the awareness that a supposedly safe drug can still cause
an anaphylactic shock.
Schlüsselwörter
Ticagrelor - Anaphylaxie - Myokardinfarkt - unerwünschte Arzneimittelwirkung
Key words
ticagrelor - anaphylaxis - myocardial infarction - side effect
