CC BY-NC-ND 4.0 · Endosc Int Open 2019; 07(10): E1303-E1309
DOI: 10.1055/a-0996-8089
Original article
Owner and Copyright © Georg Thieme Verlag KG 2019

Endoscopic sleeve gastroplasty: a modified technique with greater curvature compression sutures

Michael A. Glaysher
Department of Upper Gastrointestinal Surgery, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, Hampshire, UK
,
Alma L. Moekotte
Department of Upper Gastrointestinal Surgery, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, Hampshire, UK
,
Jamie Kelly
Department of Upper Gastrointestinal Surgery, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, Hampshire, UK
› Institutsangaben
Weitere Informationen

Publikationsverlauf

submitted 19. März 2019

accepted after revision 03. Juni 2019

Publikationsdatum:
07. Oktober 2019 (online)

Abstract

Background Endoscopic sleeve gastroplasty (ESG) is rapidly becoming established as a safe and effective means of achieving substantial weight loss via the transoral route. New ESG suture patterns are emerging. Our aim was to investigate whether superior weight loss outcomes can be achieved by using a unique combination of longitudinal compression sutures and “U”-shaped sutures.

Methods This is a retrospective review of prospectively collected data of all patients undergoing ESG by a single operator in a single UK center.

Results Between January 2016 and December 2017, 32 patients (23 female) underwent ESG; n = 9 cases were completed utilizing a commonly used triangular suture pattern (“no longitudinal compression”) and n = 23 cases were completed using our unique “longitudinal compression” suture pattern. In the no compression and compression groups, the mean ages were 45 ± 12 years and 43 ± 10 years, the median baseline weights were 113.6 kg (range 82.0 – 156.4) and 107 kg (range 74.0 – 136.0), and the median baseline body mass indexes (BMIs) were 35.9 kg/m2 (range 30.9 – 43.8) and 36.5 kg/m2 (range 29.8 – 42.9), respectively. After 6 months, body weight had decreased by 21.1 kg (range, 12.2 – 34.0) in the compression group (n = 7) versus 10.8 kg (range, 7.0 – 25.8) in the no compression group (n = 5) (P = 0.042). Correspondingly, BMI decreased by 7.8 kg/m2 (range, 4.9 – 11.2) and 4.1 kg/m2 (range, 2.6 – 7.2) in each group, respectively (P = 0.019). Total body weight loss (%TBWL) was greater in the compression group at 19.5 % (range, 12.9 – 30.4 %) compared to 13.2 % (range, 6.2 – 17.1 %) in the non-compression group (P = 0.042). No significant adverse events were reported in this series.

Conclusion The technique of ESG is evolving and outcomes from endoscopic bariatric therapies continue to improve. We provide preliminary evidence of superior weight loss achieved through a modified gastroplasty suture pattern.

 
  • References

  • 1 World Health Organization. Obesity and overweight fact sheet: World Health Organization. Updated 18th October 2017. 2017 Available from: http://www.who.int/en/news-room/fact-sheets/detail/obesity-and-overweight [Accessed 1 June 2018]
  • 2 Schauer PR, Bhatt DL, Kirwan JP. et al. Bariatric surgery versus intensive medical therapy for diabetes – 5-year outcomes. NEJM 2017; 376: 641-651
  • 3 Buchwald H, Estok R, Fahrbach K. et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med 2009; 122: 248-256 e5
  • 4 Sjöström L. Review of the key results from the Swedish Obese Subjects (SOS) trial – a prospective controlled intervention study of bariatric surgery. J Intern Med 2013; 273: 219-234
  • 5 Rubino F, Nathan D, Eckel R. et al. Metabolic surgery in the treatment algorithm for type 2 diabetes: a joint statement by international diabetes organizations. Diabetes Care 2016; 39: 861-877
  • 6 Aminian A, Brethauer SA, Kirwan JP. et al. How safe is metabolic/diabetes surgery?. Diabetes Obes Metab 2015; 17: 198-201
  • 7 Afonso BB, Rosenthal R, Li KM. et al. Perceived barriers to bariatric surgery among morbidly obese patients. Surg Obes Relat Dis 2010; 6: 16-21
  • 8 Fogel R, De Fogel J, Bonilla Y. et al. Clinical experience of transoral suturing for an endoluminal vertical gastroplasty: 1-year follow-up in 64 patients. Gastrointest Endosc 2008; 68: 51-58
  • 9 Abu Dayyeh BK, Acosta A, Camilleri M. et al. Endoscopic sleeve gastroplasty alters gastric physiology and induces loss of body weight in obese individuals. Clin Gastroenterol Hepatol 2017; 15: 37-43 e1
  • 10 Lopez-Nava G, Galvao MP, Bautista-Castano I. et al. Endoscopic sleeve gastroplasty: how I do it?. Obes Surg 2015; 25: 1534-1538
  • 11 Sartoretto A, Sui Z, Hill C. et al. Endoscopic sleeve gastroplasty (ESG) is a reproducible and effective endoscopic bariatric therapy suitable for widespread clinical adoption: a large, international multicenter study. Obes Surg 2018; 28: 1812-1821
  • 12 Graus Morales J, Crespo Perez L, Marques A. et al. Modified endoscopic gastroplasty for the treatment of obesity. Surg Endosc 2018; 32: 3936-3942
  • 13 Sharaiha RZ, Kumta NA, Saumoy M. et al. Endoscopic sleeve gastroplasty significantly reduces body mass index and metabolic complications in obese patients. Clin Gastroenterol Hepatol 2017; 15: 504-510
  • 14 Saumoy M, Schneider Y, Zhou XK. et al. A single-operator learning curve analysis for the endoscopic sleeve gastroplasty. Gastrointest Endosc 2017; 87: 442-447
  • 15 Novikov AA, Afaneh C, Saumoy M. et al. Endoscopic sleeve gastroplasty, laparoscopic sleeve gastrectomy, and laparoscopic band for weight loss: how do they compare?. J Gastrointest Surg 2017; 22: 267-273
  • 16 Lopez-Nava G, Sharaiha RZ, Vargas EJ. et al. Endoscopic sleeve gastroplasty for obesity: a multicenter study of 248 patients with 24 months follow-up. Obes Surg 2017; 27: 2649-2655
  • 17 Kumar N, Abu Dayyeh BK, Lopez-Nava Breviere G. et al. Endoscopic sutured gastroplasty: procedure evolution from first-in-man cases through current technique. Surg Endosc 2017; 32: 2159-2164
  • 18 Hill C, El Zein M, Agnihotri A. et al. Endoscopic sleeve gastroplasty: the learning curve. Endosc Int Open 2017; 5: E900-E904
  • 19 Eid G. Sleeve gastrectomy revision by endoluminal sleeve plication gastroplasty: a small pilot case series. Surg Endosc 2017; 31: 4252-4255
  • 20 Lopez-Nava G, Galvao M, Bautista-Castano I. et al. Endoscopic sleeve gastroplasty with 1-year follow-up: factors predictive of success. Endosc Int Open 2016; 4: E222-E227
  • 21 Galvao-Neto MD, Grecco E, Souza TF. et al. Endoscopic sleeve gastroplasty – minimally invasive therapy for primary obesity treatment. Arq Bras Cir Dig 2016; 29: 95-97
  • 22 Sharaiha RZ, Kedia P, Kumta N. et al. Initial experience with endoscopic sleeve gastroplasty: technical success and reproducibility in the bariatric population. Endoscopy 2015; 47: 164-166
  • 23 Lopez-Nava G, Galvao MP, da Bautista-Castano I. et al. Endoscopic sleeve gastroplasty for the treatment of obesity. Endoscopy 2015; 47: 449-452
  • 24 Kumar N, Sahdala HNP, Shaikh S. et al. Mo1155 endoscopic sleeve gastroplasty for primary therapy of obesity: initial human cases. Gastroenterology 2014; 146: S571-S572
  • 25 Abu Dayyeh BK, Rajan E, Gostout CJ. Endoscopic sleeve gastroplasty: a potential endoscopic alternative to surgical sleeve gastrectomy for treatment of obesity. Gastrointest Endosc 2013; 78: 530-535
  • 26 Lopez-Nava G, Galvao M, Bautista-Castano I. et al. Endoscopic sleeve gastroplasty for obesity treatment: two years of experience. Arq Bras Cir Dig 2017; 30: 18-20
  • 27 Alqahtani A, Al-Darwish A, Mahmoud AE. et al. Short-term outcomes of endoscopic sleeve gastroplasty in 1000 consecutive patients. Gastrointest Endosc 2019; 89: 1132-1138