Zusammenfassung
Diese Übersichtsarbeit präsentiert den aktuellen evidenzbasierten Wissensstand über
chronische Pankreatitis aus chirurgischer Sicht. Eine praxisorientierte Zusammenfassung
der therapeutischen Strategie wird entsprechend den gültigen Leitlinien unter Berücksichtigung
der neuesten Erkenntnisse aus der Literatur dargestellt.
Abstract
Continuously rising incidence and prevalence, frequent hospitalisation, development
of opioid dependence, and early retirement of young people demonstrate the enormous
socioeconomic impact of chronic pancreatitis. Aims of therapy include pain relief,
improved quality of life, management of complications, cancer prevention and preservation
of function. Since medical and endoscopic approaches of conservative therapy have
proved to be ineffective on the long term, surgery remains the mainstay of treatment
and should be considered as early as possible. Surgery encompasses a wide spectrum
of methods, ranging from simple drainage procedures and conventional resections to
various hybrid techniques. The choice of optimal surgical management should consider
the unique pathomorphologic changes of every individual patient and be performed at
a high-volume pancreas center. This review presents the current evidence-based state
of knowledge about chronic pancreatitis from a surgical point of view with a practical
summary of therapeutic strategies according to the available guidelines and considering
most recent literature input.
Schlüsselwörter
chronische Pankreatitis - chronisches Schmerzsyndrom - Pankreasinsuffizienz - duodenumerhaltende
Pankreaskopfresektion - Duodeno-Hemipankreatektomie - Pankreatektomie
Key words
chronic pancreatitis - chronic pain - pancreatic insufficiency - duodenum-preserving
pancreatic head resection - pancreaticoduodenectomy - pancreatectomy
