Abdominal Applications of 4D Flow MRI

Christoph Riedel; Alexander Lenz; Lutz Fischer; Jun Li; Feilix Piecha; Johannes Kluwe; Gerhard Adam; Peter Bannas

doi:10.1055/a-1271-7405

RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, Inhaltsverzeichnis

Rofo 2021; 193(04): 388-398
DOI: 10.1055/a-1271-7405

Review

Abdominal Applications of 4D Flow MRI

Abdominelle Anwendungen der 4D-Fluss-MRT

Christoph Riedel

¹Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

,

Alexander Lenz

¹Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

,

Lutz Fischer

²Department of Visceral Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

,

Jun Li

²Department of Visceral Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

³Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

,

Feilix Piecha

⁴I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

,

Johannes Kluwe

⁴I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

,

Gerhard Adam

¹Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

,

Peter Bannas

¹Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

› Institutsangaben

Abstract

Background Four-dimensional flow magnetic resonance imaging (4D flow MRI) provides volumetric and time-resolved visualization and quantification of blood flow. This review presents an overview of possible applications of 4D flow MRI for non-invasive assessment of abdominal hemodynamics.

Method This review is based on the authors’ experience and the current literature. A PubMed database literature research was performed in December 2019 focusing on abdominal applications of 4D flow MRI. We illustrated the review with exemplary figures and movies of clinical cases from our institution.

Results and Conclusion 4D flow MRI offers the possibility of comprehensive assessment of abdominal blood flows in different vascular territories and organ systems. Results of recent studies indicate that 4D flow MRI improves understanding of altered hemodynamics in patients with abdominal disease and may be useful for monitoring therapeutic response. Future studies with larger cohorts aiming to integrate 4D flow MRI in the clinical routine setting are needed.

Key Points:

4D flow MRI enables comprehensive visualization of the complex abdominal vasculature
4D flow MRI enables quantification of abdominal blood flow velocities and flow rates
4D flow MRI may enable deeper understanding of altered hemodynamics in abdominal disease
Further validation studies are needed prior to broad distribution of abdominal 4D flow MRI

Citation Format

Riedel C, Lenz A, Fischer L et al. Abdominal Applications of 4D Flow MRI. Fortschr Röntgenstr 2021; 193: 388 – 398

Zusammenfassung

Hintergrund Die 4-dimensionale Fluss-Magnetresonanztomografie (4D-Fluss-MRT) erlaubt die zeitaufgelöste Darstellung und Quantifizierung des Blutflusses. Diese Übersichtsarbeit stellt die möglichen Anwendungen der 4D-Fluss-MRT zur nichtinvasiven Bildgebung der Hämodynamik im Abdomen zusammen.

Methode Diese Übersichtsarbeit basiert auf der Erfahrung der Autoren sowie einer aktuellen Literaturrecherche. Die Literaturrecherche wurde in der PubMed-Datenbank bezüglich abdomineller Anwendungen der 4D-Fluss-MRT im Dezember 2019 durchgeführt. Wir haben die Arbeit mit Abbildungen und Filmen klinischer Fälle aus unserer Institution illustriert.

Ergebnisse und Schlussfolgerung Die 4D-Fluss-MRT erlaubt die umfassende Beurteilung des abdominellen Blutflusses in verschiedenen Organsystemen und Gefäßterritorien. Die Ergebnisse neuerer Studien zeigen, dass die 4D-Fluss-MRT ein besseres Verständnis der veränderten Hämodynamik bei Patienten mit abdominellen Erkrankungen sowie die Überwachung des therapeutischen Ansprechens ermöglicht. Zukünftige Studien in größeren Kohorten sind nötig, um die 4D-Fluss-MRT in den klinischen Alltag zu integrieren.

Kernaussagen:

Die 4D-Fluss-MRT ermöglicht eine umfassende Visualisierung der komplexen abdominellen Gefäßanatomie.
Die 4D-Fluss-MRT ermöglicht die Quantifizierung der Geschwindigkeiten und der Flussraten in abdominellen Blutgefäßen.
Die 4D-Fluss-MRT könnte zu einem besseren Verständnis der veränderten Hämodynamik bei unterschiedlichen abdominellen Erkrankungen beitragen.
Weitere Studien zur Validierung der 4D-Fluss-MRT in der abdominellen Bildgebung sind vor der breiten Anwendung notwendig.

Key words

MRI - phase contrast MRI - 4D flow MRI - flow imaging - abdominal hemodynamics

Volltext

Referenzen

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