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Endoscopy 2021; 53(07): 744-748
DOI: 10.1055/a-1276-6452
Innovations and brief communications

Endoscopic ischemic polypectomy for small-bowel polyps in patients with Peutz–Jeghers syndrome

Tsevelnorov Khurelbaatar
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
2   Department of Gastroenterology, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
,
Hirotsugu Sakamoto
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
,
Tomonori Yano
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
,
Yuichi Sagara
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
,
Ulzii Dashnyam
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
3   Department of Pediatrics, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
,
Satoshi Shinozaki
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
4   Shinozaki Medical Clinic, Utsunomiya, Japan
,
Keijiro Sunada
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
,
Alan Kawarai Lefor
5   Department of Surgery, Jichi Medical University, Tochigi, Japan
,
Hironori Yamamoto
1   Department of Medicine, Division of Gastroenterology, Jichi Medical University, Tochigi, Japan
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Referred to by:

Difficult scientific evaluation of rare disease management: Peutz–Jeghers syndromeEndoscopy 2021; 53(07): 749-750
DOI: 10.1055/a-1337-2576

Referred to by:

Author commentary on Tsevelnorov Khurelbaatar et al.Endoscopy 2021; 53(07): v36-v36
DOI: 10.1055/a-1310-1130

Abstract

Background To decrease the risk of bleeding or perforation, ischemic polypectomy is performed using a detachable snare or endoclip with double-balloon endoscopy (DBE) for small-bowel polyps in patients with Peutz – Jeghers syndrome. The aim of this study was to determine the effectiveness and feasibility of ischemic polypectomy.

Methods We retrospectively reviewed patients who underwent two or more sessions of ischemic polypectomy using DBE from July 2004 to August 2017.

Results 67 therapeutic DBEs were performed in nine patients during the study period and 352 polyps were treated. The median observation period was 34 months (range 12 – 66). There was a declining trend over time in the median number of polyps > 15 mm treated per patient first DBE session 6, second 2, third 1.5, fourth 0.5, fifth 0.5; P = 0.11, Friedman test). No patient required laparotomy due to intussusception during the study period. One patient developed mild acute pancreatitis after the procedure.

Conclusions Ischemic polypectomy was feasible for the control of small-bowel polyps in patients with Peutz – Jeghers syndrome.



Publication History

Received: 09 September 2020

Accepted: 01 October 2020

Accepted Manuscript online:
01 October 2020

Article published online:
16 December 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
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