Lokal fortgeschrittenes Rektumkarzinom: neue Konzepte multimodaler Therapien

Die Behandlungsstrategien beim lokal fortgeschrittenen Rektumkarzinom sind stark im Wandel. Die in den Leitlinien empfohlene Therapie einer neoadjuvanten Radio(chemo)therapie, gefolgt von Chirurgie und ggf. adjuvanter Therapie, wird zunehmend zugunsten neuer Konzepte verlassen. Im vorliegenden Beitrag werden ausgehend vom leitlinienbasierten Status quo aktuelle Strategien und Studienkonzepte diskutiert.

Schlüsselwörter

Rektumkarzinom - perioperative Therapie - totale neoadjuvante Therapie - Oxaliplatin

• Literatur

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