CC BY-NC-ND 4.0 · Ultrasound Int Open 2021; 07(01): E2-E5
DOI: 10.1055/a-1471-6907
Case Report

Klebsiella Pneumoniae Liver Abscess Syndrome – A Challenge for Contrast-Enhanced Ultrasound

Tobias Bielow
1  Division of Gastroenterology, Department of Medicine II, University Hospital Leipzig, Leipzig, Germany
,
Valentin Blank
1  Division of Gastroenterology, Department of Medicine II, University Hospital Leipzig, Leipzig, Germany
,
Sabine Opitz
2  Institute of Pathology, Department of Diagnostics, University Hospital Leipzig, Leipzig, Germany
,
Holger Gößmann
3  Department of Diagnostic and Interventional Radiology, University Hospital Leipzig, Leipzig, Germany
,
Martin Hecker
1  Division of Gastroenterology, Department of Medicine II, University Hospital Leipzig, Leipzig, Germany
,
Daniel Seehofer
4  Visceral, Transplant, Thoracic und Vascular Surgery Center, University Hospital Leipzig, Leipzig, Germany
,
Christoph Lübbert
5  Division of Infectious Diseases and Tropical Medicine, Department of Medicine II, University Hospital Leipzig, Leipzig, Germany
,
Thomas Karlas
1  Division of Gastroenterology, Department of Medicine II, University Hospital Leipzig, Leipzig, Germany
› Author Affiliations

Introduction

Invasive liver abscess syndrome (ILAS) is caused by strains of hypervirulent Klebsiella pneumoniae (hvKp) and has emerged as the leading cause of liver abscesses in immuno-competent patients (L.K. Siu et al. Lancet Infect Dis 2012; 12: 881–87). ILAS is frequently associated with metastatic spread including the eyes, lungs, and the central nervous system. The morbidity and mortality of affected patients are increased compared to liver abscesses of other origin, especially in cases with concomitant diabetes mellitus (J. E. Choby et al. J Intern Med 2020; 287(3): 283–300). Immediate diagnosis and early intervention are essential for an optimal outcome. Therefore, ultrasound plays a crucial role if hvKp is suspected. However, experience with the characteristics of such abscesses on contrast-enhanced ultrasound (CEUS) is very limited.



Publication History

Publication Date:
20 April 2021 (online)

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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